Increased plasma malondialdehyde levels in glomerular disease as determined by a fully validated HPLC method

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Increased plasma malondialdehyde levels in glomerular disease as determined by a fully validated HPLC method.

BACKGROUND Reactive oxygen species and particularly free radical induced lipid peroxidative tissue damage have been implicated in the pathogenesis of various renal diseases. Lipid peroxidation is assessed indirectly by the measurement of secondary products, such as malondialdehyde (MDA), using the widely employed thiobarbituric acid reactive substances (TBARS) method. However, this method lacks...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 1999

ISSN: 1460-2385

DOI: 10.1093/ndt/14.4.946